A great step forward:putting diseased organs to rest
In an chapter of my sci-fi novel: SummaUfo (http://summaufo.blogspot.com.Dec/10/05), I wrote and drew a futuristic medical processing. In it, a woman affected of leukemia (cancer of white blood cells, confined initially to the bone marrow -internal cavity of the bones-), is treated causing resting of her bone marrow. To such effect, the leukemia patients’cells are transferred by means of small tubes to the exterior (out of the body), toward other bone marrows (of pig or, other), in order to exhaust the cell reproductive potential and permit the rest of the bone marrow of the sick patient. Something of this, has occurred in the fast recovery of Hannah Clark, an English girl of 12 years 
in which her old heart affected of cardiomiopathy -done not remove after a transplant - and placed in rest for 10 years, worked again in adequate form with barely 5 days of physiological adecuation. Hannah, affected of an illness that excessively stretches her cardiac fibers, had at the age of 2 years, of a heart of the size of the double one of the normal thing. In these conditions, with a heart incapáble to pump adequate blood, she was submitted to cardiac surgery, in the Great Ormond Street Hospital of London. She was transplanted a heart of pig, the same one that was attached to the original organ, at the age of 2.
The thing functioned well for 10 years and to avoid the refusal they administered her by life immunosuppressant medication, what generated in her, a lymphatic cancer, happily surpassed. In the graphics – BBC Courtesy- the heart of a pig transplanted at the age of 2, appears to the right. The 2 aortas were fused and the blood that came from the lung was grasped by the 2 left auricles.. As it is supposed, disconnect the sutures of both hearts, at the age of 12 was a relatively easy task. Although the doctors calculated a prolonged recovery, Hannah surprised them, returning to her daily physical routine in barely 5 days. With Hannah some possibilities have been opened 1) a new consistent, medical technique that put to rest the affected organ with the aid of mechanical devices (that temporarily established, carry out all the work), activating again the organ, in days, weeks or, years after an adequate rest - perhaps curative- of the organ 2)
in which her old heart affected of cardiomiopathy -done not remove after a transplant - and placed in rest for 10 years, worked again in adequate form with barely 5 days of physiological adecuation. Hannah, affected of an illness that excessively stretches her cardiac fibers, had at the age of 2 years, of a heart of the size of the double one of the normal thing. In these conditions, with a heart incapáble to pump adequate blood, she was submitted to cardiac surgery, in the Great Ormond Street Hospital of London. She was transplanted a heart of pig, the same one that was attached to the original organ, at the age of 2.The thing functioned well for 10 years and to avoid the refusal they administered her by life immunosuppressant medication, what generated in her, a lymphatic cancer, happily surpassed. In the graphics – BBC Courtesy- the heart of a pig transplanted at the age of 2, appears to the right. The 2 aortas were fused and the blood that came from the lung was grasped by the 2 left auricles.. As it is supposed, disconnect the sutures of both hearts, at the age of 12 was a relatively easy task. Although the doctors calculated a prolonged recovery, Hannah surprised them, returning to her daily physical routine in barely 5 days. With Hannah some possibilities have been opened 1) a new consistent, medical technique that put to rest the affected organ with the aid of mechanical devices (that temporarily established, carry out all the work), activating again the organ, in days, weeks or, years after an adequate rest - perhaps curative- of the organ 2)
"that cryopreservatión is not the only method to conserve organs, by
long periods. Suffices with a little blood, a aseptic enviromment and certain
degree of permanent corporal temperature".
Corroborates the previous assertion, the case of the craniopagus parasiticus, in which the second head survives with a meager blood flow, being able the face to smile and toblink. By the way ¿ what happened if dispensing with the body to this extra head, it could be isolated and to supply of greater blood flow?
Gran avance: Organos enfermos en reposo.
En un capitulo de mi novela de ciencia ficción : SummaUfo (http://summaufo.blogspot.com.Dec/10/05¿Cual es el pecado?), relaté y grafiqué un futurista tratamiento médico. En él, una mujer afectada de leucemia (cáncer de células sanguineas, confinado inicialmente a la médula ósea -cavidad interna de los huesos-), es tratada haciendo reposar su médula ósea. A tal efecto, sus células leucémicas son trasladadas mediante sondas al exterior (fuera del cuerpo), hacia otras médulas óseas (de cerdo u, otras), a fin de agotar el potencial reproductivo celular y permitir el reposo de la médula ósea de la paciente enferma. Algo de esto, ha ocurrido en la velóz recuperación de Hannah Clark una niña inglesa de 12 años en la que su antiguo corazón afectado de cardiomiopatia -no removido después de un trasplante - y dejado en reposo por 10 años, volvió a trabajar en forma adecuada con apenas 5 dias de adecuacion fisiológica. Hannah, afectada de una enfermedad que adelgaza y entiesa en forma desmesurada las fibras cardiacas, disponia a los 2 años de edad, de un corazón del tamaño del doble de lo normal. En estas condiciones, con un corazón incapáz de bombear sangre adecuadamente, fué sometida a cirugía cardiaca, en el Great Ormond Street Hospital de Londres. Le transplantaron un corazón de cerdo, el mismo que fué adosado al órgano original, a los 2 años de edad.
La cosa funcionó bien durante 10 años y para evitar el rechazo le administraron de por vida medicación inmunosupresora, lo que generó en ella, un cáncer linfático, felizmente superado. En los gráficos -Cortesia BBC- el corazón de cerdo trasplantado a los 2 años, aparece a la derecha. Las 2 aortas fueron fusionadas y la sangre que provenia del pulmón era captada por las 2 auriculas izquierdas. Como se supone, desconectar las suturas de ambos corazones, a los 12 años fué tarea relativamente fácil. Aunque los médicos calcularon una recuperación prolongada Hannah, los sorprendió, retornando a sus labores fisicas habituales, en apenas 5 dias. Con Hannah se han abierto posibilidades 1) una nueva técnica médica, consistente en hacer reposar al órgano afectado con la ayuda de dispositivos mecánicos (que temporalmente implantados, realizan todo el trabajo), volviendo a activar al órgano, dias, semanas o, años después de un adecuado reposo, curativo 2) que la criopreservación no es el único método para conservar órganos, por largos periodos. Basta con un poco de sangre, un medio aséptico y cierta temperatura corporal permanente. Corrobora el aserto anterior, el caso de los craniopagus parasiticus, en los que la segunda cabeza sobrevive con un exiguo flujo sanguineo, pudiendo la cara sonreir y pestañear. A propósito ¿ que sucederia -si prescindiendo del cuerpo- a esta cabeza extra, se la pudiese aislar y surtir de mayor flujo sanguineo? Leer más:
posted by Victor Mechán Mendez at 8:02 AM
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