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Saturday, July 22, 2017

TREATING GLIOBLASTOMAS








PROLONGED REMISSIONS IN CEREBRAL TUMORS


Recent  news have reported the  possibility not only to get  prolonged remissions, but of healing of certain types of cancer, by simply copying and enhancing the normal cellular defenses of our own humanity (Shawn Hingtgen: Tumor-homing cytotoxic humaninduced neural stem cells for cancer. Therapeutic Medicine, Vol. 9 Issue 375). One more case of the correct use of natural medicine. 1) The article reports observations made in mice and humans with brain tumors (glioblastomas), in which autologous,  reprogrammed neural stem cells (NSCs), from adult  skin cells, migrate to tumor cells in response to signals (tumor homing properties), released by tumor cells, thereafter infiltrating primary and invasive foci of glioblastomas, reducing the size of tumor cells to 2% or 5% of their original size. A novel therapeutic, since surgery, chemotherapy or radiation are unable to eradicate recurrences of glioblastomas. 2) It is necessary to consider that it is difficult to obtain  autologous  NCSs,  and that NSCs from donors have the risk of rejection and other collateral events. Bagó J.R., bypassed  this risk using mouse skin fibroblasts to which he transdiferentiated  to NSCs, a process that in mice lasts 4 days. Once obtained, human NSCs are injected directly into brain   glioblastomas reducing 20 to 50 times their size, in 24-28 days. In humans, NSCs, in addition to infiltrating tumor cells, release into glioblastomas: cytotoxic therapy, gene products, proapoptotic substances, tissue necrosis alpha factor, etc., reducing 250 times the size of glioblastomas in 3 weeks (Methods 2016.Neural stem cell therapy for cancer).



REMISIONES PROLONGADAS EN TUMORES CEREBRALES

La siguiente    noticia encierra la posibilidad no solo de  lograr remisiones prolongadas, sino de   cura  de ciertos tipos de cancer,  con solo  copiar  y mejorar  las  defensas celulares normales  de nuestra propia humanidad  (Shawn Hingtgen: Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.Translational Medicine. Vol. 9 Issue 375).   Un caso mas del correcto uso de  la  medicina natural. 1)  El articulo relata observaciones realizadas en ratones y  humanos con tumores cerebrales (glioblastomas), en las que celulas madre neurales (NSCs, neural stem cell),   reprogramadas a partir de celulas autologas adultas de piel, migran   hacia las celulas tumorales  en respuesta  a señales quimiotacticas (tumor homing properties),  liberadas por las celulas tumorales, infiltrando   focos primarios e invasivos de los glioblastomas,   reduciendo   el tamaño de las celulas tumorales al  2% o 5%,  de su tamaño original.  Una novedad terapeutica,  ya que la cirugia,  quimioterapia o radiacion son incapaces de erradicar  las recurrencias de glioblastomas. 2) Hay que considerar que   es dificil  obtener  NCSs, autologas  y que las NSCs,  procedentes de donadores tienen el riesgo de rechazo y otros eventos colaterales.  Bagó J.R., obvio  este riesgo empleando fibroblastos de piel de ratones  a las que  transdiferencio a  NSCs,  un proceso  que en ratones dura  4 dias. Obtenidas,  las NSCs humanas,   son inyectadas directamente en los glioblastomas  cerebrales reduciendo   20 a 50 veces su tamaño, en 24-28 dias. En humanos, las  NSCs, aparte de  infiltrar a las  celulas tumorales,    liberan en  los glioblastomas :  terapia citotoxica,    productos geneticos, sustancias proapoptoticas, factor alfa de necrosis tisular, etc.,   reduciendo  250 veces  el tamaño de los glioblastomas   en 3 semanas (Methods. 2016.Neural stem cell therapy for cancer). Principio del formulario

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