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Saturday, September 26, 2009

CHILD LIVER TRANSPLANTATION






Many people is happy due to the successful liver transplantation performed at a 3-year girl affected by congenital hepatic cirrhosis. Her mother of 25 years old gave her 2 segments (180 g) of her liver after totally removal of the battered liver of her daughter. The operation performed in the hospital Guillermo Almenara/Lima-Peru), was performed by Dr. Carlos Chaman and lasted 15 hours. Segmental transplants are performed because children can not accommodate the huge adult livers. Before, the immune systems of children tended to reject the liver more rapidly than adults, problem solved with the use of powerful immunosuppressive drugs (cyclosporine, tacrolimus). In split liver transplants, two patients may share a liver, the smaller part goes to the child and the larger part to the adult. In recent years, survival rates have improved: 80% at 5 years. The main indications for a liver transplant include cirrhosis, acute liver failure, hepatocellular carcinoma, etc..

TRANSPLANTES HEPATICOS EN NIÑOS


Reconforta el trasplante de hígado realizado a una niña de de 3 años afecta de cirrosis hepática congénita. Su madre de 25 años le donó 2 segmentos (180 g), de su hígado implantados trás extirparle totalmente el maltrecho hígado a su hija. La operación realizada en el hospital Guillermo Almenara /Lima-Perú), duró 15 hs estuvo a cargo del Dr. Carlos Chaman. Se realizan trasplantes segmentarios porque los niños no pueden albergar los enormes hígados adultos. Antes los sistemas inmunológicos de los niños tendían a rechazar el hígado más rápidamente que el de los adultos, problema soluccionado con el empleo de potentes inmunosupresores (ciclosporina, tacrolimus). En trasplantes de hígado dividido, dos pacientes pueden compartir un hígado, la parte más pequeña vá para el niño y la parte más grande para el adulto. En los últimos años, las tasas de supervivencia han mejorado : 80% a 5 años. Las principales indicaciones para trasplantar un hígado son: cirrosis, insuficiencia hepática aguda, hepatocarcinoma, etc.

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